KINSHASA, July 7 (Xinhua) -- The Ebola outbreak in the Democratic Republic of the Congo (DRC) has deteriorated further, with confirmed deaths rising above 520 and transmission continuing in eastern hotspot areas, according to a report released Tuesday by the World Health Organization (WHO) Regional Office for Africa.
As of July 5, the DRC had reported, 1,624 confirmed cases, including 521 confirmed deaths, with the crude case fatality ratio rising to 32.1 percent, the report said.
Across the three affected countries, the DRC, Uganda and France, a total of 1,645 confirmed cases and 523 confirmed deaths had been reported, with an overall confirmed case fatality ratio of 31.8 percent. More than 12,400 contacts still required follow-up, according to the report.
The report said the outbreak in the DRC "continues to intensify," driven by sustained transmission in hotspot health zones of Ituri and North Kivu provinces, in eastern DRC, growing numbers of community deaths, and the spread of infection into previously unaffected health zones.
The report warned that deaths occurring before patients reach care remain one of the clearest signs that surveillance and referral systems are still lagging behind transmission. Among 430 confirmed deaths investigated as of July 5, 397, or 92.3 percent, occurred in the community or before admission to a treatment facility.
Contact tracing has improved but remains below the level needed to interrupt transmission rapidly. As of July 5, 12,412 contacts were under follow-up in the DRC, of whom 9,624, or 77.5 percent, had been seen within the previous 24 hours. Overall, only 32.4 percent of confirmed cases had been detected through contact follow-up, indicating that many infections were still occurring outside known contact lists.
Treatment capacity is also under pressure. The DRC has about 700 treatment and isolation beds across more than 22 Ebola treatment centers and care facilities. As of July 5, 646 patients were in isolation nationwide, and official isolation occupancy stood at about 94.2 percent.
The report said the WHO-sponsored PARTNERS clinical trial was officially launched in the DRC on July 2, becoming the first clinical trial specifically evaluating therapeutics for the Ebola Bundibugyo virus disease, for which there is currently no approved vaccine or specific treatment.
The trial is assessing the monoclonal antibody MBP134 and remdesivir, individually and in combination.
Uganda has reported no new cases during the past two weeks. As of July 5, the country had recorded 20 confirmed cases, including two deaths. Sixteen patients had recovered and two remained hospitalized. All contacts placed under follow-up in Uganda had completed the required 21-day monitoring period without new linked cases being detected.
In France, the imported laboratory-confirmed case reported to WHO on June 24 had recovered and was discharged from hospital on July 4 after two consecutive negative laboratory tests. Five passengers who had travelled on the same flight as the patient were placed under quarantine and remained asymptomatic.
The report assessed the public health risk in the DRC as "very high," saying sustained and widespread transmission continued to outpace the current response capacity. It also warned that Uganda still faced a high risk of importation due to population movement from eastern DRC, while the imported case in France highlighted the need for sustained surveillance, traveler awareness and cross-border preparedness. ■
