JERUSALEM, April 23 (Xinhua) -- Scientists have discovered a bacterial "gatekeeper" that blocks the spread of antibiotic resistance, a finding that could lead to new ways of treating stubborn infections.
Researchers at the Hebrew University of Jerusalem identified a specific protein that stops bacteria from sharing genetic material with their neighbors, the university said in statement on Thursday.
The study, published earlier this month in the journal Nature Microbiology, explains how microbes compete for resources by hoarding beneficial genes.
Bacteria typically exchange DNA through tiny bridges called nanotubes. These structures allow small DNA molecules, known as plasmids, to move between cells. Since plasmids often carry the instructions for antibiotic resistance, this exchange is a primary reason why "superbugs" evolve so quickly.
The researchers found that a protein called YokF acts as a filter. It breaks down DNA during the transfer process, effectively preventing nearby bacteria from acquiring new traits.
By understanding how bacteria naturally block these genetic "bridges," scientists hope to develop treatments that mimic the process. Slowing the speed at which resistance genes move through a population could extend the effectiveness of existing antibiotics.
The university said the discovery is particularly relevant in crowded environments where different types of microbes must compete for limited resources. ■
